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Salt-inducible kinase 2 and -3 are downregulated in adipose tissue from obese or insulin-resistant individuals: implications for insulin signalling and glucose uptake in human adipocytes

AIMS/HYPOTHESIS: Salt-inducible kinases (SIKs) are related to the metabolic regulator AMP-activated protein kinase (AMPK). SIK2 is abundant in adipose tissue. The aims of this study were to investigate the expression of SIKs in relation to human obesity and insulin resistance, and to evaluate whethe...

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Detalles Bibliográficos
Autores principales: Säll, Johanna, Pettersson, Annie M. L., Björk, Christel, Henriksson, Emma, Wasserstrom, Sebastian, Linder, Wilhelm, Zhou, Yuedan, Hansson, Ola, Andersson, Daniel P., Ekelund, Mikael, Degerman, Eva, Stenkula, Karin G., Laurencikiene, Jurga, Göransson, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518086/
https://www.ncbi.nlm.nih.gov/pubmed/27807598
http://dx.doi.org/10.1007/s00125-016-4141-y