AICAR ameliorates high-fat diet-associated pathophysiology in mouse and ex vivo models, independent of adiponectin

AIMS/HYPOTHESIS: In this study, we aimed to evaluate the therapeutic potential of 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), an activator of AMP-activated protein kinase, for ameliorating high-fat diet (HFD)-induced pathophysiology in mice. We also aimed to determine whether the benefici...

Descripción completa

Detalles Bibliográficos
Autores principales: Börgeson, Emma, Wallenius, Ville, Syed, Gulam H., Darshi, Manjula, Lantero Rodriguez, Juan, Biörserud, Christina, Ragnmark Ek, Malin, Björklund, Per, Quiding-Järbrink, Marianne, Fändriks, Lars, Godson, Catherine, Sharma, Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518112/
https://www.ncbi.nlm.nih.gov/pubmed/28188334
http://dx.doi.org/10.1007/s00125-017-4211-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518112/
https://www.ncbi.nlm.nih.gov/pubmed/28188334
http://dx.doi.org/10.1007/s00125-017-4211-9

Ejemplares similares