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T-Regulatory Cells Confer Increased Myelination and Stem Cell Activity after Stroke-Induced White Matter Injury

Stroke-induced hypoxia causes oligodendrocyte death due to inflammation, lack of oxygen and exacerbation of cell death. Bone marrow-derived stem cells (BMSCs) possess an endogenous population of T-regulatory cells (T(regs)) which reduce secretion of pro-inflammatory cytokines that lead to secondary...

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Detalles Bibliográficos
Autores principales: Zarriello, Sydney, Neal, Elliot G., Kaneko, Yuji, Borlongan, Cesario V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518209/
https://www.ncbi.nlm.nih.gov/pubmed/31010132
http://dx.doi.org/10.3390/jcm8040537