Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human IVD Cells In Vitro

Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the senescence-associated secretory phenotype (SASP) associated with inflammation and back pain. Cells from degenerate and non-mildly-degenerate human IVD were obtained from organ donors and from patients undergoin...

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Detalles Bibliográficos
Autores principales: Cherif, Hosni, Bisson, Daniel G., Jarzem, Peter, Weber, Michael, Ouellet, Jean A., Haglund, Lisbet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518239/
https://www.ncbi.nlm.nih.gov/pubmed/30934902
http://dx.doi.org/10.3390/jcm8040433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518239/
https://www.ncbi.nlm.nih.gov/pubmed/30934902
http://dx.doi.org/10.3390/jcm8040433

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