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Curcumin and o-Vanillin Exhibit Evidence of Senolytic Activity in Human IVD Cells In Vitro
Curcumin and o-Vanillin cleared senescent intervertebral disc (IVD) cells and reduced the senescence-associated secretory phenotype (SASP) associated with inflammation and back pain. Cells from degenerate and non-mildly-degenerate human IVD were obtained from organ donors and from patients undergoin...
Autores principales: | Cherif, Hosni, Bisson, Daniel G., Jarzem, Peter, Weber, Michael, Ouellet, Jean A., Haglund, Lisbet |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518239/ https://www.ncbi.nlm.nih.gov/pubmed/30934902 http://dx.doi.org/10.3390/jcm8040433 |
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