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Germline Risk Contribution to Genomic Instability in Multiple Myeloma

Genomic instability, a well-established hallmark of human cancer, is also a driving force in the natural history of multiple myeloma (MM) – a difficult to treat and in most cases fatal neoplasm of immunoglobulin producing plasma cells that reside in the hematopoietic bone marrow. Long recognized man...

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Detalles Bibliográficos
Autores principales: Janz, Siegfried, Zhan, Fenghuang, Sun, Fumou, Cheng, Yan, Pisano, Michael, Yang, Ye, Goldschmidt, Hartmut, Hari, Parameswaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518313/
https://www.ncbi.nlm.nih.gov/pubmed/31139207
http://dx.doi.org/10.3389/fgene.2019.00424