Retrotransposons in the development and progression of amyotrophic lateral sclerosis

Endogenous retrotransposon sequences constitute approximately 42% of the human genome, and mobilisation of retrotransposons has resulted in rearrangements, duplications, deletions, novel transcripts and the introduction of new regulatory domains throughout the human genome. Both germline and somatic...

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Detalles Bibliográficos
Autores principales: Savage, Abigail L, Schumann, Gerald G, Breen, Gerome, Bubb, Vivien J, Al-Chalabi, Ammar, Quinn, John P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2019
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518469/
https://www.ncbi.nlm.nih.gov/pubmed/30305322
http://dx.doi.org/10.1136/jnnp-2018-319210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518469/
https://www.ncbi.nlm.nih.gov/pubmed/30305322
http://dx.doi.org/10.1136/jnnp-2018-319210

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