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Ischemia time impacts on respiratory chain functions and Ca(2+)-handling of cardiac subsarcolemmal mitochondria subjected to ischemia reperfusion injury
BACKGROUND: Mitochondrial impairment can result from myocardial ischemia reperfusion injury (IR). Despite cardioplegic arrest, IR-associated cardiodepression is a major problem in heart surgery. We determined the effect of increasing ischemia time on the respiratory chain (RC) function, the inner me...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518521/ https://www.ncbi.nlm.nih.gov/pubmed/31088484 http://dx.doi.org/10.1186/s13019-019-0911-1 |