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In vivo continuous evolution of metabolic pathways for chemical production

Microorganisms have long been used as chemical plant to convert simple substrates into complex molecules. Various metabolic pathways have been optimised over the past few decades, but the progresses were limited due to our finite knowledge on metabolism. Evolution is a knowledge-free genetic randomi...

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Detalles Bibliográficos
Autores principales: Tan, Zheng Lin, Zheng, Xiang, Wu, Yinan, Jian, Xingjin, Xing, Xinhui, Zhang, Chong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518619/
https://www.ncbi.nlm.nih.gov/pubmed/31088458
http://dx.doi.org/10.1186/s12934-019-1132-y