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Eukaryotic initiation factor 4A2 promotes experimental metastasis and oxaliplatin resistance in colorectal cancer

BACKGROUND: Deregulation of protein translation control is a hallmark of cancers. Eukaryotic initiation factor 4A2 (EIF4A2) is required for mRNA binding to ribosome and plays an important role in translation initiation. However, little is known about its functions in colorectal cancer (CRC). METHODS...

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Detalles Bibliográficos
Autores principales: Chen, Zhan-Hong, Qi, Jing-Jing, Wu, Qi-Nian, Lu, Jia-Huan, Liu, Ze-Xian, Wang, Yun, Hu, Pei-Shan, Li, Ting, Lin, Jin-Fei, Wu, Xiang-Yuan, Miao, Lei, Zeng, Zhao-Lei, Xie, Dan, Ju, Huai-Qiang, Xu, Rui-Hua, Wang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518650/
https://www.ncbi.nlm.nih.gov/pubmed/31088567
http://dx.doi.org/10.1186/s13046-019-1178-z