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Significance of PTEN Mutation in Cellular Process, Prognosis, and Drug Selection in Clear Cell Renal Cell Carcinoma

It is well established that the PTEN (Phosphatase and Tensin Homolog) mutant is a frequently mutated gene found in clear cell renal cell carcinoma (ccRCC), making it a potential biomarker for individualized treatment opinions. Here, in the present study, we designed a method to evaluate the signific...

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Detalles Bibliográficos
Autores principales: Fan, Caibin, Zhao, Chunchun, Wang, Fei, Li, Shugen, Wang, Jianqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518664/
https://www.ncbi.nlm.nih.gov/pubmed/31139560
http://dx.doi.org/10.3389/fonc.2019.00357