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Utility of I-SceI and CCR5-ZFN nucleases in excising selectable marker genes from transgenic plants

OBJECTIVES: Removal of selection marker genes from transgenic plants is highly desirable for their regulatory approval and public acceptance. This study evaluated the use of two nucleases, the yeast homing endonuclease, I-SceI, and the designed zinc finger nuclease, CCR5-ZFN, in excising marker gene...

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Detalles Bibliográficos
Autores principales: Pathak, Bhuvan P., Pruett, Eliott, Guan, Huazhong, Srivastava, Vibha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518718/
https://www.ncbi.nlm.nih.gov/pubmed/31088537
http://dx.doi.org/10.1186/s13104-019-4304-2