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Osteopontin and its spatiotemporal relationship with glial cells in the striatum of rats treated with mitochondrial toxin 3-nitropropionic acid: possible involvement in phagocytosis

BACKGROUND: Osteopontin (OPN, SPP1) is upregulated in response to acute brain injury, and based on its immunoreactivity, two distinct forms have been identified: intracellular OPN within brain macrophages and small granular OPN, identified as OPN-coated degenerated neurites. This study investigates...

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Detalles Bibliográficos
Autores principales: Riew, Tae-Ryong, Kim, Soojin, Jin, Xuyan, Kim, Hong Lim, Lee, Jeong-Hwa, Lee, Mun-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518780/
https://www.ncbi.nlm.nih.gov/pubmed/31088570
http://dx.doi.org/10.1186/s12974-019-1489-1