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Knockdown of PKM2 enhances radiosensitivity of cervical cancer cells

BACKGROUND: Pyruvate kinase isozyme type M2 (PKM2) catalyzes the final step in glycolysis and has been found to be up-regulated in multiple human malignancies. However, whether PKM2 regulates the radiosensitivity of human cervical cancer (CC) remains unknown. METHODS: The expression of PKM2 in 94 pa...

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Detalles Bibliográficos
Autores principales: Lin, Yanzhu, Zhai, Hui, Ouyang, Yi, Lu, Zhiyuan, Chu, Chengbiao, He, Qianting, Cao, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518815/
https://www.ncbi.nlm.nih.gov/pubmed/31114449
http://dx.doi.org/10.1186/s12935-019-0845-7