Quantitative Temporal Proteomic Analysis of Vaccinia Virus Infection Reveals Regulation of Histone Deacetylases by an Interferon Antagonist

Vaccinia virus (VACV) has numerous immune evasion strategies, including multiple mechanisms of inhibition of interferon regulatory factor 3 (IRF-3), nuclear factor κB (NF-κB), and type I interferon (IFN) signaling. Here, we use highly multiplexed proteomics to quantify ∼9,000 cellular proteins and ∼...

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Detalles Bibliográficos
Autores principales: Soday, Lior, Lu, Yongxu, Albarnaz, Jonas D., Davies, Colin T.R., Antrobus, Robin, Smith, Geoffrey L., Weekes, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518873/
https://www.ncbi.nlm.nih.gov/pubmed/31067474
http://dx.doi.org/10.1016/j.celrep.2019.04.042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518873/
https://www.ncbi.nlm.nih.gov/pubmed/31067474
http://dx.doi.org/10.1016/j.celrep.2019.04.042

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