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Efficacy, long‐term safety, and impact on quality of life of elobixibat in more severe constipation: Post hoc analyses of two phase 3 trials in Japan

BACKGROUND: In two phase 3 trials, elobixibat, a locally acting ileal bile acid transporter inhibitor, resolved constipation and was well tolerated in Japanese patients with chronic constipation. We analyzed the efficacy, safety, and impact on quality of life (QOL) of elobixibat in patients with sym...

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Detalles Bibliográficos
Autores principales: Nakajima, Atsushi, Taniguchi, Shinya, Kurosu, Shinsuke, Gillberg, Per‐Göran, Mattsson, Jan P., Camilleri, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519041/
https://www.ncbi.nlm.nih.gov/pubmed/30793431
http://dx.doi.org/10.1111/nmo.13571