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PAD4-dependent NETs generation are indispensable for intestinal clearance of Citrobacter rodentium

Peptidyl arginine deiminase-4 (PAD4) is indispensable for generation of neutrophil extracellular traps (NETs), which can provide antimicrobial effects during host innate immune response; however, the role of PAD4 against gastrointestinal infection is largely unknown. Herein, we challenged PAD4-defic...

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Detalles Bibliográficos
Autores principales: Saha, Piu, Yeoh, Beng San, Xiao, Xia, Golonka, Rachel M., Singh, Vishal, Wang, Yanming, Vijay-Kumar, Matam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519124/
https://www.ncbi.nlm.nih.gov/pubmed/30710097
http://dx.doi.org/10.1038/s41385-019-0139-3