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Comprehensive Profiling of HIV Antibody Evolution

This study evaluates HIV antibody responses and their evolution during the course of HIV infection. A phage display system is used to characterize antibody binding to >3,300 HIV peptides in 57 adults with early- to late-stage infection. We find that the number of unique epitopes targeted (“antibo...

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Detalles Bibliográficos
Autores principales: Eshleman, Susan H., Laeyendecker, Oliver, Kammers, Kai, Chen, Athena, Sivay, Mariya V., Kottapalli, Sanjay, Sie, Brandon M., Yuan, Tiezheng, Monaco, Daniel R., Mohan, Divya, Wansley, Daniel, Kula, Tomasz, Morrison, Charles, Elledge, Stephen J., Brookmeyer, Ron, Ruczinski, Ingo, Larman, H. Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519133/
https://www.ncbi.nlm.nih.gov/pubmed/31042470
http://dx.doi.org/10.1016/j.celrep.2019.03.097