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Hematopoietic-Specific Deletion of Foxo1 Promotes NK Cell Specification and Proliferation

We previously reported that deletion of Foxo1, via Ncr1-iCre mice from the expression of NKp46 onward, led to enhanced natural killer (NK) cell maturation and effector function. In this model, however, the role of Foxo1 in regulating NK cell specification and early development remains exclusive. Her...

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Detalles Bibliográficos
Autores principales: Huang, Pei, Wang, Fangjie, Yang, Yao, Lai, Wenjing, Meng, Meng, Wu, Shuting, Peng, Hongyan, Wang, Lili, Zhan, Rixing, Imani, Saber, Yu, Jianhua, Chen, Bingbo, Li, Xiaohui, Deng, Youcai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519137/
https://www.ncbi.nlm.nih.gov/pubmed/31139183
http://dx.doi.org/10.3389/fimmu.2019.01016