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Hematopoietic-Specific Deletion of Foxo1 Promotes NK Cell Specification and Proliferation
We previously reported that deletion of Foxo1, via Ncr1-iCre mice from the expression of NKp46 onward, led to enhanced natural killer (NK) cell maturation and effector function. In this model, however, the role of Foxo1 in regulating NK cell specification and early development remains exclusive. Her...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519137/ https://www.ncbi.nlm.nih.gov/pubmed/31139183 http://dx.doi.org/10.3389/fimmu.2019.01016 |