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Cannabinoid Receptor 2 Agonist JWH-015 Inhibits Interleukin-1β-Induced Inflammation in Rheumatoid Arthritis Synovial Fibroblasts and in Adjuvant Induced Arthritis Rat via Glucocorticoid Receptor

Management of pain in the treatment of rheumatoid arthritis (RA) is a priority that is not fully addressed by the conventional therapies. In the present study, we evaluated the efficacy of cannabinoid receptor 2 (CB2) agonist JWH-015 using RA synovial fibroblasts (RASFs) obtained from patients diagn...

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Detalles Bibliográficos
Autores principales: Fechtner, Sabrina, Singh, Anil K., Srivastava, Ila, Szlenk, Christopher T., Muench, Tim R., Natesan, Senthil, Ahmed, Salahuddin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519139/
https://www.ncbi.nlm.nih.gov/pubmed/31139184
http://dx.doi.org/10.3389/fimmu.2019.01027