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Maintenance of the virulence plasmid in Shigella flexneri is influenced by Lon and two functional partitioning systems

Members of the genus Shigella carry a large plasmid, pINV, which is essential for virulence. In Shigella flexneri, pINV harbours three toxin‐antitoxin (TA) systems, CcdAB, GmvAT and VapBC that promote vertical transmission of the plasmid. Type II TA systems, such as those on pINV, consist of a toxic...

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Detalles Bibliográficos
Autores principales: McVicker, Gareth, Hollingshead, Sarah, Pilla, Giulia, Tang, Christoph M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519299/
https://www.ncbi.nlm.nih.gov/pubmed/30767313
http://dx.doi.org/10.1111/mmi.14225