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LXRα Promotes Hepatosteatosis in Part Through Activation of MicroRNA‐378 Transcription and Inhibition of Ppargc1β Expression

Nonalcoholic fatty liver disease (NAFLD) is a major risk factor of many end‐stage liver diseases. Alterations in microRNA expression have been reported in patients with NAFLD. However, the transcriptional mechanism(s) of dysregulated microRNAs under the state of NAFLD is poorly described, and microR...

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Detalles Bibliográficos
Autores principales: Zhang, Tianpeng, Duan, Jiangyan, Zhang, Lei, Li, Zhuoyu, Steer, Clifford J., Yan, Guiqin, Song, Guisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519356/
https://www.ncbi.nlm.nih.gov/pubmed/30281809
http://dx.doi.org/10.1002/hep.30301