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CD4CD8 Double Positive T cell responses during Mycobacterium tuberculosis infection in cynomolgus macaques

BACKGROUND: Tuberculosis (TB) kills millions of people every year. CD4 and CD8 T cells are critical in the immune response against TB. T cells expressing both CD4 and CD8 (CD4CD8 T cells) are functionally active and have not been examined in the context of TB. METHODS: We examine peripheral blood mo...

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Detalles Bibliográficos
Autores principales: Diedrich, Collin Richard, Gideon, Hannah Priyadarshini, Rutledge, Tara, Baranowski, Tonilynn Marie, Maiello, Pauline, Myers, Amy J., Lin, Philana Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519377/
https://www.ncbi.nlm.nih.gov/pubmed/30723927
http://dx.doi.org/10.1111/jmp.12399