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Identification of RNase-sensitive LINE-1 Ribonucleoprotein Interactionsby Differential Affinity Immobilization

Long Interspersed Nuclear Element-1 (LINE-1, L1) constitutes a family of autonomous, self-replicating genetic elements known as retrotransposons. Although most are inactive, copious L1 sequences populate the human genome. L1s proliferate in a ‘copy-and-paste’ fashion through an RNA intermediate; a f...

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Detalles Bibliográficos
Autores principales: Jiang, Hua, Taylor, Martin S., Molloy, Kelly R., Altukhov, Ilya, LaCava, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bio-Protocol 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519465/
https://www.ncbi.nlm.nih.gov/pubmed/31106238
http://dx.doi.org/10.21769/BioProtoc.3200