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The neuron-specific interleukin-1 receptor accessory protein alters emergent network state properties in Vitro

Small in vitro neuronal/glial networks exhibit sleep-like states. Sleep regulatory substance interleukin-1β (IL1) signals via its type I receptor and a receptor accessory protein (AcP). AcP has a neuron-specific isoform called AcPb. After sleep deprivation, AcPb, but not AcP, upregulates in brain, a...

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Detalles Bibliográficos
Autores principales: Nguyen, Joseph T., Sahabandu, Dinuka, Taishi, Ping, Xue, Mengran, Jewett, Kathryn, Dykstra-Aiello, Cheryl, Roy, Sandip, Krueger, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519741/
https://www.ncbi.nlm.nih.gov/pubmed/31106280
http://dx.doi.org/10.1016/j.nbscr.2019.01.002