One-step generation of modular CAR-T with AAV-Cpf1

Enhancing production efficiency, stability, effector function, and other desired features is of prime interest for chimeric antigen receptor engineered T cells (CAR-Ts). Here, we developed a new system for efficient generation of CAR-T with significantly enhanced features by streamlined genome engin...

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Detalles Bibliográficos
Autores principales: Dai, Xiaoyun, Park, Jonathan J., Du, Yaying, Kim, Hyunu R., Wang, Guangchuan, Errami, Youssef, Chen, Sidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519746/
https://www.ncbi.nlm.nih.gov/pubmed/30804551
http://dx.doi.org/10.1038/s41592-019-0329-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519746/
https://www.ncbi.nlm.nih.gov/pubmed/30804551
http://dx.doi.org/10.1038/s41592-019-0329-7

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