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Maternal Nanos inhibits Importin-α2/Pendulin-dependent nuclear import to prevent somatic gene expression in the Drosophila germline

Repression of somatic gene expression in germline progenitors is one of the critical mechanisms involved in establishing the germ/soma dichotomy. In Drosophila, the maternal Nanos (Nos) and Polar granule component (Pgc) proteins are required for repression of somatic gene expression in the primordia...

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Detalles Bibliográficos
Autores principales: Asaoka, Miho, Hanyu-Nakamura, Kazuko, Nakamura, Akira, Kobayashi, Satoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519790/
https://www.ncbi.nlm.nih.gov/pubmed/31091233
http://dx.doi.org/10.1371/journal.pgen.1008090