Thrombin-cleaved syndecan-3/-4 ectodomain fragments mediate endothelial barrier dysfunction

OBJECTIVE: The endothelial glycocalyx constitutes part of the endothelial barrier but its degradation leaves endothelial cells exposed to transmigrating cells and circulating mediators that can damage the barrier or promote intercellular gaps. Syndecan proteins are key components of the endothelial...

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Detalles Bibliográficos
Autores principales: Jannaway, Melanie, Yang, Xiaoyuan, Meegan, Jamie E., Coleman, Danielle C., Yuan, Sarah Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519803/
https://www.ncbi.nlm.nih.gov/pubmed/31091226
http://dx.doi.org/10.1371/journal.pone.0214737

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519803/
https://www.ncbi.nlm.nih.gov/pubmed/31091226
http://dx.doi.org/10.1371/journal.pone.0214737

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