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Thrombin-cleaved syndecan-3/-4 ectodomain fragments mediate endothelial barrier dysfunction
OBJECTIVE: The endothelial glycocalyx constitutes part of the endothelial barrier but its degradation leaves endothelial cells exposed to transmigrating cells and circulating mediators that can damage the barrier or promote intercellular gaps. Syndecan proteins are key components of the endothelial...
Autores principales: | Jannaway, Melanie, Yang, Xiaoyuan, Meegan, Jamie E., Coleman, Danielle C., Yuan, Sarah Y. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519803/ https://www.ncbi.nlm.nih.gov/pubmed/31091226 http://dx.doi.org/10.1371/journal.pone.0214737 |
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