HLA alleles, especially amino-acid signatures of HLA-DPB1, might contribute to the molecular pathogenesis of early-onset autoimmune thyroid disease

The major histocompatibility complex region has been suggested to play an important role in the development of autoimmune thyroid disease (AITD). In this study, we investigated the associations of human leukocyte antigen (HLA) alleles and amino acid variants of HLA with early-onset AITD. HLA class I...

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Detalles Bibliográficos
Autores principales: Shin, Dong-Hwan, Baek, In-Cheol, Kim, Hyung Jae, Choi, Eun-Jeong, Ahn, Moonbae, Jung, Min Ho, Suh, Byung-Kyu, Cho, Won Kyoung, Kim, Tai-Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519818/
https://www.ncbi.nlm.nih.gov/pubmed/31091281
http://dx.doi.org/10.1371/journal.pone.0216941

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519818/
https://www.ncbi.nlm.nih.gov/pubmed/31091281
http://dx.doi.org/10.1371/journal.pone.0216941

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