Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its in vivo pharmacokinetic evaluation in Beagle dogs

Gastroretentive (GR) systems are designed to prolong gastric residence time to allow sustained absorption and improve the oral bioavailability of drugs with a narrow absorption window in the upper part of the gastrointestinal tract. The present study aimed to develop a GR system for acyclovir using...

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Detalles Bibliográficos
Autores principales: Shin, Soyoung, Kim, Tae Hwan, Jeong, Seok Won, Chung, Seung Eun, Lee, Da Young, Kim, Do-Hyung, Shin, Beom Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519832/
https://www.ncbi.nlm.nih.gov/pubmed/31091273
http://dx.doi.org/10.1371/journal.pone.0216875

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519832/
https://www.ncbi.nlm.nih.gov/pubmed/31091273
http://dx.doi.org/10.1371/journal.pone.0216875

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