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Development of a gastroretentive delivery system for acyclovir by 3D printing technology and its in vivo pharmacokinetic evaluation in Beagle dogs
Gastroretentive (GR) systems are designed to prolong gastric residence time to allow sustained absorption and improve the oral bioavailability of drugs with a narrow absorption window in the upper part of the gastrointestinal tract. The present study aimed to develop a GR system for acyclovir using...
Autores principales: | Shin, Soyoung, Kim, Tae Hwan, Jeong, Seok Won, Chung, Seung Eun, Lee, Da Young, Kim, Do-Hyung, Shin, Beom Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519832/ https://www.ncbi.nlm.nih.gov/pubmed/31091273 http://dx.doi.org/10.1371/journal.pone.0216875 |
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