Cargando…
Genetic lesioning of histamine neurons increases sleep–wake fragmentation and reveals their contribution to modafinil-induced wakefulness
Acute chemogenetic inhibition of histamine (HA) neurons in adult mice induced nonrapid eye movement (NREM) sleep with an increased delta power. By contrast, selective genetic lesioning of HA neurons with caspase in adult mice exhibited a normal sleep–wake cycle overall, except at the diurnal start o...
Autores principales: | Yu, Xiao, Ma, Ying, Harding, Edward C, Yustos, Raquel, Vyssotski, Alexei L, Franks, Nicholas P, Wisden, William |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519916/ https://www.ncbi.nlm.nih.gov/pubmed/30722053 http://dx.doi.org/10.1093/sleep/zsz031 |
Ejemplares similares
-
Corrigendum: Genetic lesioning of histamine neurons increases sleep–wake fragmentation and reveals their contribution to modafinil-induced wakefulness
por: Yu, Xiao, et al.
Publicado: (2019) -
Neurotransmitters of sleep and wakefulness in flatworms
por: Omond, Shauni E T, et al.
Publicado: (2022) -
Quiet wakefulness: the influence of intraperitoneal and intranasal oxytocin on sleep–wake behavior and neurophysiology in rats
por: Raymond, Joel S, et al.
Publicado: (2023) -
Histamine: neural circuits and new medications
por: Scammell, Thomas E, et al.
Publicado: (2018) -
The relationship between fasting-induced torpor, sleep, and wakefulness in laboratory mice
por: Huang, Yi-Ge, et al.
Publicado: (2021)