The Cas4-Cas1-Cas2 complex mediates precise prespacer processing during CRISPR adaptation

CRISPR adaptation immunizes bacteria and archaea against viruses. During adaptation, the Cas1-Cas2 complex integrates fragments of invader DNA as spacers in the CRISPR array. Recently, an additional protein Cas4 has been implicated in selection and processing of prespacer substrates for Cas1-Cas2, a...

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Detalles Bibliográficos
Autores principales: Lee, Hayun, Dhingra, Yukti, Sashital, Dipali G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519985/
https://www.ncbi.nlm.nih.gov/pubmed/31021314
http://dx.doi.org/10.7554/eLife.44248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519985/
https://www.ncbi.nlm.nih.gov/pubmed/31021314
http://dx.doi.org/10.7554/eLife.44248

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