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Cooperative impact of thiazolidinedione and fatty acid synthase on human osteogenesis

Previous, we found that the small molecules capable of inhibiting the expression and the pro-adipogenic activity of ZNF521 might improve the osteogenic performance of aging human bone marrow MSCs (bmMSCs), and that fatty acid synthase (FASN) was a critical effector of ZNF521’s pro-adipogenic activit...

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Detalles Bibliográficos
Autores principales: Chen, Ching-Yun, Tseng, Kuo-Yun, Wong, Zhe-Hong, Chen, Ya-Ping, Chen, Ting-Yu, Chen, Hsuan-Ying, Chen, Zih-Ying, Lin, Feng-Huei, Wu, Hung-Ming, Lin, Shankung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519991/
https://www.ncbi.nlm.nih.gov/pubmed/31005954
http://dx.doi.org/10.18632/aging.101916