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A role of the 53BP1 protein in genome protection: structural and functional characteristics of 53BP1-dependent DNA repair

Nuclear architecture plays a significant role in DNA repair mechanisms. It is evident that proteins involved in DNA repair are compartmentalized in not only spontaneously occurring DNA lesions or ionizing radiation-induced foci (IRIF), but a specific clustering of these proteins can also be observed...

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Detalles Bibliográficos
Autores principales: Bártová, Eva, Legartová, Soňa, Dundr, Miroslav, Suchánková, Jana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6519998/
https://www.ncbi.nlm.nih.gov/pubmed/30996128
http://dx.doi.org/10.18632/aging.101917