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Epigenetic control of Foxp3 in intratumoral T-cells regulates growth of hepatocellular carcinoma
Capability of tumor cells to impede immune response are largely associated with their interaction and regulation of CD4+CD25+ forkhead box transcription factor (Foxp)3+ regulatory T (Treg) cells, which suppress cytotoxic T cell-mediated immunity in the tumor microenvironment. Foxp3 level is critical...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520002/ https://www.ncbi.nlm.nih.gov/pubmed/31006654 http://dx.doi.org/10.18632/aging.101918 |