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Epigenetic control of Foxp3 in intratumoral T-cells regulates growth of hepatocellular carcinoma

Capability of tumor cells to impede immune response are largely associated with their interaction and regulation of CD4+CD25+ forkhead box transcription factor (Foxp)3+ regulatory T (Treg) cells, which suppress cytotoxic T cell-mediated immunity in the tumor microenvironment. Foxp3 level is critical...

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Detalles Bibliográficos
Autores principales: Liu, Qin, Du, Fang, Huang, Wei, Ding, Xiaoyi, Wang, Zhongmin, Yan, Fuhua, Wu, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520002/
https://www.ncbi.nlm.nih.gov/pubmed/31006654
http://dx.doi.org/10.18632/aging.101918