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Impaired ribosome biogenesis: mechanisms and relevance to cancer and aging

The biosynthesis of ribosomes is a complex process that requires the coordinated action of many factors and a huge energy investment from the cell. Ribosomes are essential for protein production, and thus for cellular survival, growth and proliferation. Ribosome biogenesis is initiated in the nucleo...

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Detalles Bibliográficos
Autores principales: Turi, Zsofia, Lacey, Matthew, Mistrik, Martin, Moudry, Pavel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520011/
https://www.ncbi.nlm.nih.gov/pubmed/31026227
http://dx.doi.org/10.18632/aging.101922