PES1 is a critical component of telomerase assembly and regulates cellular senescence

Telomerase defers the onset of telomere shortening and cellular senescence by adding telomeric repeat DNA to chromosome ends, and its activation contributes to carcinogenesis. Telomerase minimally consists of the telomerase reverse transcriptase (TERT) and the telomerase RNA (TR). However, how telom...

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Detalles Bibliográficos
Autores principales: Cheng, Long, Yuan, Bin, Ying, Sunyang, Niu, Chang, Mai, Hongxu, Guan, Xin, Yang, Xiaohui, Teng, Yan, Lin, Jing, Huang, Junjian, Jin, Rui, Wu, Jun, Liu, Bo, Chang, Shaohong, Wang, Enqun, Zhang, Chunxia, Hou, Ning, Cheng, Xuan, Xu, Danyang, Yang, Xiao, Gao, Shan, Ye, Qinong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520020/
https://www.ncbi.nlm.nih.gov/pubmed/31106266
http://dx.doi.org/10.1126/sciadv.aav1090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520020/
https://www.ncbi.nlm.nih.gov/pubmed/31106266
http://dx.doi.org/10.1126/sciadv.aav1090

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