Transcriptional and functional consequences of TP53 splice mutations in colorectal cancer

TP53 mutations are common in colorectal cancer (CRC). Most TP53 sequencing studies have been restricted to coding regions, but recent studies have revealed that splice mutations can generate transcript variants with distinct tumorigenic and prognostic properties. Here, we performed unrestricted sequ...

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Detalles Bibliográficos
Autores principales: Smeby, Jørgen, Sveen, Anita, Eilertsen, Ina A., Danielsen, Stine A., Hoff, Andreas M., Eide, Peter W., Johannessen, Bjarne, Hektoen, Merete, Skotheim, Rolf I., Guren, Marianne G., Nesbakken, Arild, Lothe, Ragnhild A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520361/
https://www.ncbi.nlm.nih.gov/pubmed/31092812
http://dx.doi.org/10.1038/s41389-019-0141-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520361/
https://www.ncbi.nlm.nih.gov/pubmed/31092812
http://dx.doi.org/10.1038/s41389-019-0141-3

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