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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production

Mast cells contribute to the pathology of allergic and other disorders. Strategies to interfere with harmful mast cell-related activities are therefore warranted. Previously we established a principle for inducing selective apoptosis of mast cells, by the use of lysosomotropic agents that cause secr...

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Detalles Bibliográficos
Autores principales: Paivandy, Aida, Eriksson, Jens, Melo, Fabio Rabelo, Sellin, Mikael E., Pejler, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520368/
https://www.ncbi.nlm.nih.gov/pubmed/31123601
http://dx.doi.org/10.1038/s41420-019-0177-3