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Lysosomotropic challenge of mast cells causes intra-granular reactive oxygen species production
Mast cells contribute to the pathology of allergic and other disorders. Strategies to interfere with harmful mast cell-related activities are therefore warranted. Previously we established a principle for inducing selective apoptosis of mast cells, by the use of lysosomotropic agents that cause secr...
Autores principales: | Paivandy, Aida, Eriksson, Jens, Melo, Fabio Rabelo, Sellin, Mikael E., Pejler, Gunnar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520368/ https://www.ncbi.nlm.nih.gov/pubmed/31123601 http://dx.doi.org/10.1038/s41420-019-0177-3 |
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