Aquaporin 4 inhibition alters chemokine receptor expression and T cell trafficking

Aquaporins (AQPs) are water channels that mediate a variety of biological processes. However, their role in the immune system is poorly understood. We recently reported that AQP4 is expressed by naïve and memory T cells and that AQP4 blockade with a small molecule inhibitor prolongs murine heart all...

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Detalles Bibliográficos
Autores principales: Nicosia, Michael, Miyairi, Satoshi, Beavers, Ashley, Farr, George W., McGuirk, Paul R., Pelletier, Marc F., Valujskikh, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520372/
https://www.ncbi.nlm.nih.gov/pubmed/31092872
http://dx.doi.org/10.1038/s41598-019-43884-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520372/
https://www.ncbi.nlm.nih.gov/pubmed/31092872
http://dx.doi.org/10.1038/s41598-019-43884-2

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