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Aquaporin 4 inhibition alters chemokine receptor expression and T cell trafficking
Aquaporins (AQPs) are water channels that mediate a variety of biological processes. However, their role in the immune system is poorly understood. We recently reported that AQP4 is expressed by naïve and memory T cells and that AQP4 blockade with a small molecule inhibitor prolongs murine heart all...
Autores principales: | Nicosia, Michael, Miyairi, Satoshi, Beavers, Ashley, Farr, George W., McGuirk, Paul R., Pelletier, Marc F., Valujskikh, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520372/ https://www.ncbi.nlm.nih.gov/pubmed/31092872 http://dx.doi.org/10.1038/s41598-019-43884-2 |
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