The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage

The accumulation of fibroblasts is a critical step in the development of fibrosis, and lysophosphatidic acid (LPA) promotes fibrosis by regulating multiple fibroblast functions. Autotaxin (ATX) is a key LPA-producing enzyme, and we hypothesized that ATX contributes to the development of renal inters...

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Detalles Bibliográficos
Autores principales: Sakai, Norihiko, Bain, Gretchen, Furuichi, Kengo, Iwata, Yasunori, Nakamura, Miki, Hara, Akinori, Kitajima, Shinji, Sagara, Akihiro, Miyake, Taito, Toyama, Tadashi, Sato, Koichi, Nakagawa, Shiori, Shimizu, Miho, Kaneko, Shuichi, Wada, Takashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520387/
https://www.ncbi.nlm.nih.gov/pubmed/31092842
http://dx.doi.org/10.1038/s41598-019-43576-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520387/
https://www.ncbi.nlm.nih.gov/pubmed/31092842
http://dx.doi.org/10.1038/s41598-019-43576-x

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