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The involvement of autotaxin in renal interstitial fibrosis through regulation of fibroblast functions and induction of vascular leakage

The accumulation of fibroblasts is a critical step in the development of fibrosis, and lysophosphatidic acid (LPA) promotes fibrosis by regulating multiple fibroblast functions. Autotaxin (ATX) is a key LPA-producing enzyme, and we hypothesized that ATX contributes to the development of renal inters...

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Detalles Bibliográficos
Autores principales:	Sakai, Norihiko, Bain, Gretchen, Furuichi, Kengo, Iwata, Yasunori, Nakamura, Miki, Hara, Akinori, Kitajima, Shinji, Sagara, Akihiro, Miyake, Taito, Toyama, Tadashi, Sato, Koichi, Nakagawa, Shiori, Shimizu, Miho, Kaneko, Shuichi, Wada, Takashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520387/ https://www.ncbi.nlm.nih.gov/pubmed/31092842 http://dx.doi.org/10.1038/s41598-019-43576-x

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