Early Steps in Herpes Simplex Virus Infection Blocked by a Proteasome Inhibitor

Viruses commandeer host cell 26S proteasome activity to promote viral entry, gene expression, replication, assembly, and egress. Proteasomal degradation activity is critical for herpes simplex virus (HSV) infection. The proteasome inhibitor bortezomib (also known as Velcade and PS-341) is a clinical...

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Detalles Bibliográficos
Autores principales: Schneider, Seth M., Pritchard, Suzanne M., Wudiri, George A., Trammell, Chasity E., Nicola, Anthony V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520451/
https://www.ncbi.nlm.nih.gov/pubmed/31088925
http://dx.doi.org/10.1128/mBio.00732-19

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520451/
https://www.ncbi.nlm.nih.gov/pubmed/31088925
http://dx.doi.org/10.1128/mBio.00732-19

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