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Therapeutic Potential of Multifunctional Tacrine Analogues

Abstract: Tacrine is a potent inhibitor of cholinesterases (acetylcholinesterase and butyrylcholinesterase) that shows limiting clinical application by liver toxicity. In spite of this, analogues of tacrine are considered as a model inhibitor of cholinesterases in the therapy of Alzheimer’s disease....

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Detalles Bibliográficos
Autores principales: Przybyłowska, Maja, Kowalski, Szymon, Dzierzbicka, Krystyna, Inkielewicz-Stepniak, Iwona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520589/
https://www.ncbi.nlm.nih.gov/pubmed/29651948
http://dx.doi.org/10.2174/1570159X16666180412091908