Thiamine and benfotiamine protect neuroblastoma cells against paraquat and β-amyloid toxicity by a coenzyme-independent mechanism

BACKGROUND: Benfotiamine (BFT) is a synthetic thiamine precursor with high bioavailability. It is efficient in treating complications of type 2 diabetes and has beneficial effects in mouse models of neurodegenerative diseases. The mechanism of action of BFT remains unknown, though it is sometimes su...

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Detalles Bibliográficos
Autores principales: Sambon, Margaux, Napp, Aurore, Demelenne, Alice, Vignisse, Julie, Wins, Pierre, Fillet, Marianne, Bettendorff, Lucien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520661/
https://www.ncbi.nlm.nih.gov/pubmed/31193162
http://dx.doi.org/10.1016/j.heliyon.2019.e01710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520661/
https://www.ncbi.nlm.nih.gov/pubmed/31193162
http://dx.doi.org/10.1016/j.heliyon.2019.e01710

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