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Understanding Prion Strains: Evidence from Studies of the Disease Forms Affecting Humans

Prion diseases are a unique group of rare neurodegenerative disorders characterized by tissue deposition of heterogeneous aggregates of abnormally folded protease-resistant prion protein (PrP(Sc)), a broad spectrum of disease phenotypes and a variable efficiency of disease propagation in vivo. The d...

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Detalles Bibliográficos
Autores principales: Rossi, Marcello, Baiardi, Simone, Parchi, Piero
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520670/
https://www.ncbi.nlm.nih.gov/pubmed/30934971
http://dx.doi.org/10.3390/v11040309